Scientific News

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News from the global scientific community focused on furthering the understanding and treatment of pediculosis, including research and clinical trials.

03.10.17 | Detection of bacterial pathogens including potential new species in human head lice from Mali

A new study has assessed the occurrence of bacterial pathogens from head lice collected in two rural villages from Mali, and identified for the first time, the presence of the DNA of two pathogenic bacteria, namely Coxiella burnetii (5.1%) and Rickettsia aeschlimannii (0.6%) detected in human head lice.

03.10.17 | Pyrethroids inhibit K2P channels and activate sensory neurons: basis of insecticide-induced paraesthesias

A new study has examined the effect of pyrethroids such as permethrin or tetramethrin (TM) on two-pore domain potassium (K2P) channels mainly expressed in sensory neurons and suggested that inhibition of K2P channels facilitates sensory neuron activation and increases their excitability which contributes to the generation of paraesthesias and pain after parathyroid exposure.

03.10.17 | Detoxification of ivermectin by ATP binding cassette transporter C4 and cytochrome P450 monooxygenase 6CJ1 in the human body louse, Pediculus humanus humanus

A new study investigating the functional properties of ivermectin-induced detoxification genes suggests that ATP binding cassette transporter C4 (PhABCC4) and cytochrome P450 6CJ1 (CYP6CJ1) are involved in the Phase III and Phase I xenobiotic metabolism of ivermectin respectively.

09.06.17 | Ivermectin lipid-based nanocarriers as novel formulations against head lice

A new study investigating the insecticidal activity of ivermectin-loaded lipid nanocapsules (IVM-LNC) against permethrin-resistant head lice has highlighted the effectiveness in the encapsulation of ivermectin (IVM) into stable LNC dispersion with a potential clinical activity against head lice .

08.06.17 | Identification of Novel Voltage-Gated Sodium Channel Mutations in Human Head and Body Lice

A new study investigating louse populations from Iran has revealed that 100% of all specimens collected from the Provinces of West-Azerbaijan and Zanjan have at least one of six novel mutations potentially associated with kdr resistance in body and head lice.

07.05.17 | Novel polymeric micelles for insect pest control: encapsulation of essential oil monoterpenes inside a triblock copolymer shell for head lice control

A new study has investigated the pediculicidal activity of micellar systems containing a 5 wt% of poloxamer 407 and 1.25 wt% of the different monoterpenes using an ex vivo immersion test and revealed that aqueous formulations are effective against head lice with mortality ranging from 30 to 60%.

16.02.17 | Arrestant Effect of Human Scalp Components on Head Louse Behaviour

A new study analysing the effect of human scalp components on the behavior of adult head lice has shown for the first time the effect of host components conditioning on head lice behavior.

16.02.17 | Head Lice of Pygmies Reveal the Presence of Relapsing Fever Borreliae

A molecular screening of pygmies’ head lice in the Republic of Congo has identified the presence of a dangerous human pathogen, Borrelia reccurentis, the causative agent of relapsing fever, in ten clade A head lice, which was not reported in the republic of Congo and B. theileri in one head louse.

14.11.16 | New Insights into the Origin of Clade B Lice

A new study analysing the ancient DNA of head lice and their eggs from the Roman period has revealed that clade B lice existed, at least in the Middle East, prior to contacts between Native Americans and Europeans.

14.10.16 | FDA Finalises Head Lice Guidance

In an effort to control the head lice infestations and drug resistance to the most commonly used head lice treatments, the US Food and Drug Administration (FDA) has issued a new guidance on developing topical drugs.

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